Skip to main content

Charles River to buy CiToxLab

18th February 2019

Submitted by:

Andrew Warmington

Charles River Laboratories (CRL) has agreed to acquire CiToxLab in a €448 million merger that will create the largest player in the early stage CRO space for the pharmaceuticals industry. The deal is expected to close in Q2, subject to labour consultations, regulatory requirements and customary closing conditions.

 

CiToxLab is itself a relatively recent creation out of M&A activity. It has nine operating sites in six countries in Europe and North America – most obviously France, Canada and Hungary - with global capacity totalling over 65,000 m2. It offers a wide range of non-clinical CRO services, notably regulated safety assessment services, non-regulated discovery services, and medical device testing.

 

“The proposed acquisition would expand and solidify CRL’s position as the partner of choice for our clients’ early-stage research needs, at a time when we believe there continues to be significant demand for outsourced services from both biotechnology and pharmaceutical companies,” said James Foster, CEO, chairman and president of CRL.

 

The strategic rationale, CRL said, is that adding CiToxLab would strengthen its presence in growing end markets, its global scale, its geographic footprint and its scientific capabilities. It would also expand the company’s client base, particularly in its fastest-growing segment of small and mid-sized biotech. Furthermore, the combination is expected to enhance CRL’s portfolio in four key areas:

  • general and speciality toxicology, including developmental and reproductive toxicology and ocular services, and agricultural and industrial chemical testing, including ecotoxicology services of all kinds
  • pre-clinical medical device testing services
  • non-regulated discovery services
  • genomics research, adding expertise in this field to CRL’s mechanistic and investigative toxicology knowledge

The acquisition is expected to add $115-130 million to CRL’s 2019 consolidated revenue. CiToxLab’s revenue is expected to grow at a high-single-digit rate. This is said to be in line with the long-term organic revenue growth target for the Discovery & Safety Assessment segment of CRL, of which it will form a part.

UPL to split out specialities

Indian agrochemicals giant UPL has announced plans to transfer its speciality chemicals business, including agrochemical

Submitted by:

Andrew Warmington

AI for SAPs

Together with Algo Artis, Japan’s Nippon Shokubai has developed an algorithm-based means for the production

Submitted by:

Andrew Warmington

Axplora's site at Vizag

Axplora expands in India

Axplora has announced a “significant” investment at its site in Vizag, India (pictured)

Submitted by:

Andrew Warmington

Regis' headquarters in Chicago

Esteve acquires Regis

 

Barcelona-based Esteve Química has acquired Regis Technologies, a hitherto privately owned CDMO headquartered in Chicago

Submitted by:

Andrew Warmington

Meribel's facility at Uppsala

Ofichem buys site in Sweden

Netherlands-based CDMO Ofichem has acquired Meribel Pharma Solutions’ former Recipharm site in Uppsala, Sweden, which

Submitted by:

Andrew Warmington

Nippon Shokubai's API Facility in Japan

Nucleic acid API boost

Nippon Shokubai is to expand its GMP capacity for nucleic APIs tenfold It will install

Submitted by:

Andrew Warmington

Flamma's facility in Dalian

Flamma opens in China

Italian CDMO Flamma Group has officially opened its new cGMP plant at Dalian, China, where

Submitted by:

Andrew Warmington

Afyren Neoxy plant

Milestones for two greentech firms

Afyren has achieved continuous production at its Afyren Neoxy plant at Clermont-Ferrand (pictured)

Submitted by:

Andrew Warmington

Origin by Ocean derives its materials from sargassum

CABB in algae biorefinery deal

CABB has agreed a strategic partnership to establish a first-in-kind algae biorefinery at its site at Kokkola

Submitted by:

Andrew Warmington

First waste-based biosurfactants

Belgian start-up AmphiStar has launched what it claims are the first fully upcycled biobased surfactants

Submitted by:

Andrew Warmington

Aether to supply Seqens

Indian firm Aether Industries has entered into a manufacturing agreement with Chemoxy International, a UK-based

Submitted by:

Andrew Warmington

New model for biocatalysts

BASF, the Austrian Research Centre of Industrial Biotechnology (ACIB) and the University of Graz in

Submitted by:

Andrew Warmington

CBE JU funds 31 more projects

The Circular Bio-based Europe Joint Undertaking (CBE JU), a €2 billion partnership between the EU

Submitted by:

Andrew Warmington

Ribbon cutting ceremony at Lubrizol's new office

Lubrizol opens London office

Lubrizol has opened a new office in Hammersmith, London. This will be home to a

Submitted by:

Andrew Warmington

Sudarshan to buy Heubach

India’s Sudarshan Chemical Industries (SCIL) has entered into a definitive agreement to acquire the Heubach

Submitted by:

Andrew Warmington

Alliance in natural fragrances

Sensegen, a US-based specialist in biotech-enabled fragrances, notably a new class of natural musk raw

Submitted by:

Andrew Warmington

Croda breaks ground in China

Croda International has broken ground for a low-carbon, multi-purpose production facility on a greenfield site

Submitted by:

Andrew Warmington

CCT collaboration for Givaudan

Flavours and fragrances giant Givaudan has agreed a research collaboration for the development of sustainable

Submitted by:

Andrew Warmington

REACH Authorisation

Candidate List ‘reaches’ 250

The European Chemicals Agency (ECHA) has added three more substances to the Candidate List of

Submitted by:

Andrew Warmington

Staff at Brenntag's newly acquired Czech site

CO2-free distribution site first

Brenntag has officially inaugurated what it claims to be the first CO2-emission-free chemical distribution site

Submitted by:

Andrew Warmington